b'From left: James D. Allred, MD; NTION VE SS & PRE LLNE WEKenneth C. Hilty, MDTwo examples are Kenneth C. Hilty, MD, who serves as medical director and clinical lipidologist of the Advanced Lipid Disorders and Cardiovascular Risk Reduction Clinic, and James D. Allred, MD, a cardiologist, electrophysiologist and the director of the Atrial Fibrillation Center.THE FIGHT AGAINST HIGH CHOLESTEROLLipid management can be tricky. Thats where Dr. Hilty can help. Actively involved in clinical research, he and his team offer a variety of advanced treatments to combat high cholesterol. I help people unable to tolerate cholesterol-lowering drugs such as statins by trying otherproven approaches or sometimes by using other medications entirely, Dr. Hilty says. Up until five years ago, we had CLINICS limited options beyond statins. WithWith new new molecular technologies and antibody therapies, we are able to treat more patients than ever andmolecular extend their lives.technologies Recently, a groundbreaking trial in 2019 called REDUCE- and antibody THAT Cone Healths specialtyIT proved that up to four gramstherapies, daily of the purified Omega-3 EPA could cut cardiovascularwe are able clinics offer advancedevents by 2030% when pairedto treat more care tailored to eachwith statins. This effect was not seen with over-the-counter fish oils. patients than CARE patients unique needs.Cone Health patients may beever and CARE Learn more about theeligible for one of four clinical trials extend their of groundbreaking treatments that lower AFib and Lipid clinics. cholesterol in those for whom standarddrugs work poorly or arent strong enough. lives.These include the 2019 ORION trial that uses KENNETH C.molecular technology to halve LDL (low-density lipoprotein, HILTY, MDor bad cholesterol) through twice-yearly injections.Another trial called VESALIUS-CV blocks a major cholesterol-controlling protein called PCSK9 using an antibody therapy. The AEGIS-II study relies on purified plasma A s the nations top killer, cardiovascular disease is linked to risk factorsprotein from donors that can help stabilize and possibly oust existing arterial plaque. like high cholesterol and abnormal heart rhythms that can go undetected until theAn additional trial thwarts cholesterol metabolism in the liver through novel RNA conditions are advanced and harder to resolve. therapies, aiming to reduce high blood triglycerides. Thats why it pays to seek specialists in targeted cardiology fields, such as those at ConeGenetic therapies arent far down the road, Dr. Hilty says. Already, we canHealth. Its clinics tout teams of doctors, surgeons, nurse practitioners, nurses, dietitians,look more deeply into a patients lipid profile with lipoprotein particle testing, which pharmacists, genetic counselors and other specialists.examines not only cholesterol levels but also the size, type and distribution of lipid Areas of focus include heart failure, electrophysiology and atrial fibrillation, hypertension,particles that directly impact the chance of developing cardiovascular disease. And high cholesterol, and womens heart health. The clinics provide high-level care catering togenetic screening allows us to identify persons at risk for familial hyperlipidemia (FH) each patients unique needs and are led by top specialists in the field of cardiology. and hopefully improve a familys cardiac disease risk for generations. 30 / CONE HEALTH HEART & VASCULAR / 31'